A journal that publishes papers on a broad range of topics of general interest to those working on the nervous system
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Journal of Neuroscience recent issues
Phospho-CREB Regulation on NMDA Glutamate Receptor 2B and Mitochondrial Calcium Uniporter in the Ventrolateral Periaqueductal Gray Controls Chronic Morphine Withdrawal in Male Rats
Opioid use disorder (OUD) is a chronic disease of the brain, and it currently continues at crisis proportions in the United States. Opioid physical withdrawal is a major driver of compulsive drug-taking behavior, triggering short-term relapse of o...
Author: Yi, H., Gu, J., Hamilton, P. J., Liu, S., Zhu, S., Ikegami, D., Hayashi, K., Kashiwagi, Y., Iida, T., Liu, Q., Zhu, X., Tong, X., Peng, D., Zhuang, G. Z., Pardo, M., El-Rifai, W., Levitt, R. C., Nestler, E. J., Hao, S.
Posted: July 16, 2025, 4:30 pm
HDAC3 Serine 424 Phospho-mimic and Phospho-null Mutants Bidirectionally Modulate Long-Term Memory Formation and Synaptic Plasticity in the Adult and Aging Mouse Brain
Long-term memory (LTM) formation is negatively regulated by histone deacetylase 3 (HDAC3), a transcriptional repressor. Emerging evidence suggests that posttranslational phosphorylation of HDAC3 at its serine 424 (S424) residue is critical for its...
Author: Rodriguez, A. C., Kramar, E. A., Augustynski, A. S., Keiser, A. A., Dong, T. N., Jones, T. S., Vakilian, S. N., Patel, S. T., Rounds, J. S., Chinn, C. A., Kwapis, J. L., Matheos, D. P., Wood, M. A.
Posted: July 16, 2025, 4:30 pm
Oddball Evoked Deviant Responses Reflect Complex Context-Dependent Expectations in Mouse V1
Evoked responses in the mouse primary visual cortex can be modulated by the temporal context in which visual inputs are presented. Oddball stimuli embedded in a sequence of regularly repeated visual elements have been shown to drive relatively lar...
Author: Knudstrup, S. G., Reyes, C. M., Jensen, C. M., Schecter, R. W., Frank, M. K., Gavornik, J. P.
Posted: July 16, 2025, 4:30 pm
Neuropathic Pain-Like Responses in a Chronic CNS Injury Model Are Mediated by Corticospinal-Targeted Spinal Interneurons
Chronic neuropathic pain is a persistent and debilitating outcome of traumatic central nervous system injury, affecting up to 80% of individuals. Postinjury pain is refractory to treatments due to the limited understanding of the brain–spinal cord...
Author: Guan, X., Zhu, Y., Zhong, J., Hollis, E.
Posted: July 16, 2025, 4:30 pm
V2b Neurons Act via Multiple Targets to Produce in Phase Inhibition during Locomotion
Spinal interneurons shape motor neuron activity. Gata3+ V2b neurons are a major inhibitory spinal population. These neurons are present at multiple spinal levels in mice, suggesting an important function in motor control. In zebrafish, our previou...
Author: Sengupta, M., Bertram, A., Zhu, S. I., Goodhill, G. J., Bagnall, M. W.
Posted: July 16, 2025, 4:30 pm
Erratum: Ostroff et al., "Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies"
Author:
Posted: July 16, 2025, 4:30 pm
A Normative Account of 3D Motion Perception from Natural Scenes
Author: Xu, Z.-X.
Posted: July 16, 2025, 4:30 pm
Positron Emission Tomography (PET) Neuroimaging of the Pink1-/- Rat Parkinson Disease Model with the Norepinephrine Transporter (NET) Ligand [18F]NS12137
Evidence suggests that the neurotransmitter norepinephrine may play an important role in Parkinson disease (PD). The norepinephrine transporter (NET) regulates noradrenergic signaling and can serve as an index of noradrenergic innervation in neuro...
Author: Converse, A. K., Krasko, M. N., Rudisch, D. M., Slesarev, M. S., Szot, J. C., Gallagher, C. L., Ciucci, M. R.
Posted: July 16, 2025, 4:30 pm
