A journal that publishes papers on a broad range of topics of general interest to those working on the nervous system
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Journal of Neuroscience recent issues
Functional and Regional Specificity of Noradrenergic Signaling for Encoding and Retrieval of Associative Recognition Memory in the Rat
Recognition of a familiar object in a novel location requires retrieval of the former object–place association and encoding of novel information. Such object-in-place (OiP) memory recruits a neural network including the hippocampus (HPC), medial p...
Author: Tran, S., Barker, G. R. I., Mathiasen, M. L., Aggleton, J. P., Warburton, E. C.
Posted: June 11, 2025, 4:30 pm
CXCL12 Engages Cortical Inhibitory Neurons to Enhance Dendritic Spine Plasticity and Structured Network Activity
The chemokine CXCL12 is a highly conserved peptide that regulates homeostatic processes in the brain throughout life. Recent work shows that CXCL12 increases dendritic spine density in cortical neurons, which requires activation of CXCL12's recept...
Author: Ho, C., Luchetta, J., Nash, B., Festa, L. K., Johnson, J. A., Sacan, A., Jackson, J. G., Sanz-Clemente, A., Brandimarti, R., Meucci, O.
Posted: June 11, 2025, 4:30 pm
Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors
In humans, mutations or deletions of atypical FAT cadherin genes are linked to autism spectrum disorder and cerebellar ataxia. However, their large genomic size and the enormous size of their encoded proteins have hampered functional studies, leav...
Author: Wang, X., Pu, Y., Miao, J., Xie, L., Guan, L., Cui, Y., Wang, J., Qin, L., Han, Y., Wöhr, M., Zhang, B.
Posted: June 11, 2025, 4:30 pm
Zooming In and Out: Selective Attention Modulates Color Signals in Early Visual Cortex for Narrow and Broad Ranges of Task-Relevant Features
Research on feature-based attention has shown that selecting a specific visual feature (e.g., the color red) results in enhanced processing in early visual cortex, providing the neural basis for the efficient identification of relevant features in...
Author: Özkan, M., Chapman, A. F., Störmer, V. S.
Posted: June 11, 2025, 4:30 pm
Sex Differences in Histamine Regulation of Striatal Dopamine
Dopamine modulation of the basal ganglia differs in males and females and is implicated in numerous neuropsychiatric conditions, including some, like Tourette syndrome (TS) and attention deficit hyperactivity disorder (ADHD), that have marked sex ...
Author: Van Zandt, M., Pittenger, C.
Posted: June 11, 2025, 4:30 pm
Target Selection Signals Causally Influence Human Perceptual Decision-Making
The ability to form decisions is a foundational cognitive function which is impaired across many psychiatric and neurological conditions. Understanding the neural processes underpinning clinical deficits may provide insights into the fundamental m...
Author: Pearce, D. J., Loughnane, G. M., Chong, T. T.- J., Demeyere, N., Mattingley, J. B., Moore, M. J., New, P. W., OConnell, R. G., ONeill, M. H., Rangelov, D., Stolwyk, R. J., Webb, S. S., Zhou, S.-H., Brosnan, M. B., Bellgrove, M. A.
Posted: June 11, 2025, 4:30 pm
PVN-NAc Shell-VP Circuit OT and OTR Neurons Regulate Pair Bonding via D2R and D1R
Previous studies have found that several neurochemicals are involved in formation of pair bonding. However, the circuit mechanisms underlying pair bonding, especially how these chemicals interact in this circuit to regulate pair bonding, remain un...
Author: Zhang, L., Qu, Y., Li, L., Sun, Y., Qian, W., Xiao, J., Huang, K., Han, X., Niu, H., Li, L., Liu, J., Qiao, H., Jia, R., Lian, T., He, Z., Tai, F.
Posted: June 11, 2025, 4:30 pm
The Neurobiology of Cognitive Fatigue and Its Influence on Effort-Based Choice
Feelings of cognitive fatigue emerge through repeated mental exertion and are ubiquitous in our daily lives. However, there is a limited understanding of the neurobiological mechanisms underlying the influence of cognitive fatigue on decisions to ...
Author: Steward, G., Looi, V., Chib, V. S.
Posted: June 11, 2025, 4:30 pm