A journal that publishes papers on a broad range of topics of general interest to those working on the nervous system
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Journal of Neuroscience recent issues
Annual Renewal: Why the Society for Neuroscience Meeting Keeps Drawing Me Back
Registering for my 35th consecutive Society for Neuroscience Annual Meeting in early July 2025, I realized the Conference is the longest standing yearly ritual of my life. I couldn't help wondering, why do I keep doing it? Is it duty or desire, an...
Author: Raman, I. M.
Posted: October 1, 2025, 4:30 pm
Stopping Muscle Contractions and Relaxations during Action Inhibition Involves Global and Targeted Control Dependent on Muscle State
The mechanisms underpinning the stopping of muscle contractions and relaxations during action inhibition remain unclear. Central stop commands may be targeted and act on task-active muscles only, or instead be global, acting on task-passive muscle...
Author: De Havas, J., Ibanez, J., Gomi, H., Bestmann, S.
Posted: October 1, 2025, 4:30 pm
The Somatostatin Pathway Projected from the Basal Forebrain to the Lateral Habenula Promotes Isoflurane Anesthesia Recovery
The basal forebrain (BF) acts as a pivotal relay station in the transmission of arousal signals, projecting to both cortical and subcortical structures. Among its downstream targets is the lateral habenula (LHb), which recent research has implicat...
Author: Wang, Y., Wang, Z., Xu, M., Wang, J., Cai, S., Zheng, D., Tang, A., Yu, T., Wang, Y., Luo, T., Yu, S.
Posted: October 1, 2025, 4:30 pm
Mechanisms of Long-Term Nonexternally Reinforced Preference Change: Functional Connectivity Changes in a Longitudinal Functional MRI Study
Behavioral change studies mostly focus on external reinforcements to modify preferences. Cue-approach training (CAT) is a paradigm that influences preferences by the mere association of stimuli, sensory cues, and a rapid motor response, without ex...
Author: Itzkovitch, A., Oren, S., Chopra, S., Fornito, A., Schonberg, T.
Posted: October 1, 2025, 4:30 pm
Beta and High Gamma Oscillations in the Cortico-striatal Network Reflect Reward Certainty on a Probabilistic Reversal Learning Task
Behavioral outcomes are rarely certain, requiring subjects to discriminate between available choices by using feedback to guide future decisions. Probabilistic reversal learning (PRL) tasks test subjects’ ability to learn and flexibly adapt to cha...
Author: Koloski, M. F., Salimi, M., Hulyalkar, S., Tang, T., Barnes, S. A., Mishra, J., Ramanathan, D. S.
Posted: October 1, 2025, 4:30 pm
PolyQ-Expansion of Ataxin-2 Disrupts Microtubule Stability and Impairs Axon Outgrowth
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by mislocalization and aggregation of proteins in motor neurons. Ataxin-2 (ATXN2), an RNA-binding protein harboring 22-polyglutamine (polyQ) repeats, is a risk ...
Author: Kim, S. K., Gelfand, V. I.
Posted: October 1, 2025, 4:30 pm
Disrupted Calcium Dynamics in Reactive Astrocytes Occur with End Feet-Arteriole Decoupling in an Amyloid Mouse Model of Alzheimer's Disease
While cerebrovascular dysfunction and reactive astrocytosis are extensively characterized hallmarks of Alzheimer's disease (AD) and related dementias, the dynamic relationship between reactive astrocytes and cerebral vessels remains poorly underst...
Author: Weiss, B. E., Gant, J. C., Lin, R.-L., Gollihue, J. L., Rogers, C. B., Kraner, S. D., Rucker, E. B., Katsumata, Y., Jiang, Y., Nelson, P. T., Wilcock, D. M., Sompol, P., Thibault, O., Norris, C. M.
Posted: October 1, 2025, 4:30 pm
mWAKE in the Central Amygdala Regulates Fear Learning and Memory
The central amygdala (CeA) is an important neuronal hub that integrates external sensory inputs and information about internal states to regulate a range of innate and learned behaviors, including fear learning and memory. Prior studies, leveragin...
Author: Xiong, J., Mehta, A., Liu, Q., Luo, A. X., Li, P. P., Janak, P. H., Wu, M. N.
Posted: October 1, 2025, 4:30 pm
