A journal that publishes papers on a broad range of topics of general interest to those working on the nervous system
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Journal of Neuroscience recent issues
Multi-omics Analysis Reveals miR-7220-5p Alleviates N2O Addictive Behaviors via NR2B/ERK/CREB Signaling
Nitrous oxide use disorder (NUD) has recently received increasing social concern for its sharp rise among young people. However, the underlying mechanisms of NUD remain largely unexplored, which obstructs treatment strategy development and may exa...
Author: Yang, T., Chen, Y., Wang, M., Ren, R., Yan, F., Xu, P., Di, B.
Posted: August 13, 2025, 4:30 pm
Erratum: Pachitariu et al., "Robustness of Spike Deconvolution for Neuronal Calcium Imaging"
Author:
Posted: August 13, 2025, 4:30 pm
Disruption of grin2A, an Epilepsy-Associated Gene, Produces Altered Spontaneous Swim Behavior in Zebrafish
N-Methyl-d-aspartate receptors (NMDARs) control synaptic plasticity and brain development in a manner determined by receptor subunit composition. Pathogenic variants in GRIN2A gene, encoding the NMDAR GluN2A subunit, can cause gain or loss of func...
Author: Abramova, V., Tomovic, E., Kysilov, B., Korinek, M., Dobrovolski, M., Krausova, B. H., Fili, K., Abdel Rahman, F. E. S., Bozikova, P., Cerny, J., Smejkalova, T., Balik, A., Vyklicky, L.
Posted: August 13, 2025, 4:30 pm
Activation of Dopamine D1 Receptors at the Axon Initial Segment-Like Process of Retinal AII Amacrine Cells Modulates Action Potential Firing
Dopamine is an important neuromodulator found throughout the central nervous system that can influence neural circuits involved in sensory, motor, and cognitive functions. In the retina, dopamine is released by specific amacrine cells and plays a ...
Author: Veruki, M. L., Liu, J. H., Singh, J. B., Luppi, M. S., Hartveit, E.
Posted: August 13, 2025, 4:30 pm
Identification of New Ciliary Signaling Pathways in the Brain and Insights into Neurological Disorders
Primary cilia are conserved sensory hubs essential for signaling transduction and embryonic development. Ciliary dysfunction causes a variety of developmental syndromes with neurological features and cognitive impairment whose basis mostly remains...
Author: Loukil, A., Ebright, E., Hamdi, K., Menzel, E., Uezu, A., Gao, Y., Soderling, S. H., Goetz, S. C.
Posted: August 13, 2025, 4:30 pm
Synchronous Rhythmic Activity in Area V4 Can Impair Shape Detection and Neuronal Reliability
Rhythms at a population level are a defining characteristic of both normal and pathological cortical activities, but it is unclear how such rhythms interact with the activity of specific neurons to impact task performance on a trial-by-trial basis...
Author: Wahlberg, R., Netoff, T. I., Ghose, G. M.
Posted: August 13, 2025, 4:30 pm
Motor Sequence Learning Involves Better Prediction of the Next Action and Optimization of Movement Trajectories
Learning new sequential movements is a fundamental skill for many animals. Motor sequence learning may arise from three distinct processes: (1) improved execution of individual movements independent of their sequential context; (2) enhanced antici...
Author: Kashefi, M., Diedrichsen, J., Pruszynski, J. A.
Posted: August 13, 2025, 4:30 pm
Neddylation E1 Obligatory Subunit Nae1 Is Critical to Neuromuscular Junction Development and Maintenance
Rapsyn is a scaffold protein that is thought to anchor acetylcholine receptors at the neuromuscular junction (NMJ). We showed that it may be an E3 ligase that regulates NMJ development by neddylation. To obtain genetical evidence, we mutated Nae1 ...
Author: Jing, H., Wu, M., Xing, G., Lin, D., Chen, P., Li, L., Yu, Z., Zhang, H., Wang, H., Su, H., Xiong, W.-C., Mei, L.
Posted: August 13, 2025, 4:30 pm
