The goals of SLEEP Advances are to disseminate timely developments and advances that reflect the diversity of sleep and circadian science
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SLEEP Advances Current Issue
Bridging the gap between lab and field sleep studies: a proof-of-concept for studying wild rats in semi-captive environments
AbstractSleep is a vital and universal behavior distinct from mere inactivity, yet its ecological role remains poorly understood due to methodological limitations in recording sleep in the wild. Using a small, low-power biologger, collecting brain...
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Posted: July 10, 2025, 12:00 am
Neurophysiological effects of targeting sleep spindles with closed-loop auditory stimulation
AbstractSleep spindles are neural events unique to nonrapid eye movement sleep that play key roles in memory reactivation and consolidation. However, much of the evidence for their function remains correlational rather than causal. Closed-loop bra...
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Posted: July 7, 2025, 12:00 am
Cognitive behavioral therapy for insomnia among heavy-drinking veterans: a randomized pilot trial
AbstractStudy ObjectivesTwo in five Veterans report symptoms of insomnia, with higher rates among those who drink heavily. Although Cognitive Behavioral Therapy for Insomnia (CBT-I) has demonstrated efficacy among those with Alcohol Use Disorder, ...
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Posted: June 10, 2025, 12:00 am
Association of nocturnal hypoxemia and white blood cell count in a multicenter cohort
AbstractStudy ObjectivesThere is a higher risk of cardiovascular disease (CVD) in patients with obstructive sleep apnea (OSA) and innate immunity is a potential pathophysiologic pathway. The objective of this study was to determine whether nocturn...
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Posted: June 9, 2025, 12:00 am
The effects of acute trazodone administration on sleep in mice
AbstractStudy ObjectivesTrazodone is an antidepressant with robust hypnotic effects, frequently prescribed off-label to treat insomnia. Trazodone has gained recent attention in the context of neurodegenerative diseases because sleep has been propo...
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Posted: May 28, 2025, 12:00 am
Reactivation fails to offer the improvement sleep does
AbstractIn a dynamic process that ultimately affords memories their persistence, memory reconsolidation can serve to strengthen associations following reactivation, particularly in sleep, where active processes may effect overnight enhancement. Re...
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Posted: May 24, 2025, 12:00 am
Targeted memory reactivation during REM sleep may selectively enhance the late positive potential amplitude in previously encountered negative images: preliminary findings
AbstractThe function of rapid eye movement (REM) sleep in consolidating emotional memories and reducing emotional charge has been studied, but evidence remains conflicting. Our study employed the targeted memory reactivation (TMR) technique, which...
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Posted: May 24, 2025, 12:00 am
Being in the right place at the right time
AbstractThis paper is a review of my life as a sleep researcher and clinician. I chanced into sleep by being at the right place at the right time. Over the last 45 years, I became an expert on sleep and circadian rhythms in aging, in Alzheimer’s d...
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Posted: May 21, 2025, 12:00 am
