The goals of SLEEP Advances are to disseminate timely developments and advances that reflect the diversity of sleep and circadian science
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SLEEP Advances Current Issue
The CHARMS study: rationale and study protocol for an observational study of sleep and biobehavioral rhythms in older adult couples
AbstractIndividuals with mild cognitive impairment (MCI) demonstrate cognitive decline without major functional impairment and are at increased risk for developing Alzheimer’s disease and related dementias (ADRD). Sleep and biobehavioral rhythm di...
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Posted: August 30, 2025, 12:00 am
Associations between a novel measure of sleep health and cognitive functioning in middle childhood: a crosssectional Environmental Influences on Child Health Outcomes cohort study
AbstractStudy ObjectivesResearch linking children’s sleep to cognitive outcomes is inconsistent and has largely focused on one aspect of sleep, such as duration, rather than measuring multiple dimensions of sleep health. We hypothesized that child...
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Posted: August 18, 2025, 12:00 am
Home-based dim light melatonin onset assessment among adults with obesity: feasibility and procedural considerations
AbstractStudy ObjectivesDim light melatonin onset (DLMO) is the best-established marker of central circadian phase and may contribute to unraveling the role of the circadian system in obesity. This study evaluated DLMO among individuals with obesi...
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Posted: July 28, 2025, 12:00 am
Understanding discrepancies between self-reported and objective sleep in adolescents and young adults with subacute concussion
AbstractStudy ObjectivesConduct a multidimensional analysis of sleep perception, objective sleep, and neuropsychiatric wellbeing in individuals with subacute concussion compared to controls.MethodsThirty-one recently concussed individuals complete...
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Posted: July 26, 2025, 12:00 am
Preliminary investigation of obstructive sleep apnea and Alzheimer’s disease in down syndrome
AbstractThis study provided a preliminary examination of indices of obstructive sleep apsnea (OSA) and sleep disruptions in adults with Down syndrome (DS), and their associations with Alzheimer’s disease (AD) pathology and symptomatology. A total ...
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Posted: July 23, 2025, 12:00 am
Homeostatic forces underlying the daily pattern of sleep propensity
AbstractThe mismatch between rising sleep need and the fluctuating ability to fall asleep underlies insomnia—the most common sleep disorder—yet remains poorly understood. While sleep need increases steadily with time awake, sleep propensity—the li...
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Posted: July 21, 2025, 12:00 am
Sleep disordered breathing and circulating non-esterified fatty acids: the cardiovascular health study
AbstractStudy ObjectivesCirculating non-esterified fatty acids (NEFAs) have been associated with impaired glucose metabolism but their modifiable determinants remain uncertain. We sought to determine the association between objectively-measured sl...
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Posted: July 3, 2025, 12:00 am
ARC genotype modulates slow wave sleep and spectral power in the sleep EEG after total sleep deprivation
AbstractStudy ObjectivesThere are large individual differences in the homeostatic response to sleep deprivation, as reflected in slow wave sleep (SWS) and electroencephalogram (EEG) spectral power, which have largely been left unexplained. Recent ...
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Posted: June 23, 2025, 12:00 am