The mission of SLEEP® is to publish innovative, high-impact research findings in sleep and circadian science across the basic, translational, and clinical research spectrum.
Latest topics of this journal:
Sleep Current Issue
Beyond conventional polysomnography: advanced sleep feature engineering and machine learning for differentiating central disorders of hypersomnolence
The diagnosis of central disorders of hypersomnolence (CDH) remains challenging because, at present, only narcolepsy type 1 (NT1) has established diagnostic hallmarks, namely low cerebrospinal fluid hypocretin-1 levels and/or cataplexy. In contras...
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Posted: January 6, 2026, 12:00 am
The source of the Nile
Herodotus in the 5th century BCE called the Nile River Delta the “gift,” describing its tributaries, wetlands, and populated islands, and told of its glories, in particular the library at Alexandria where all knowledge was recorded. Much later, ex...
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Posted: December 22, 2025, 12:00 am
Inference, controls, and replication in the study of sleep and metabolism
Sleep oscillationsglucose metabolismsleep spindlesslow oscillationsinteraction
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Posted: December 18, 2025, 12:00 am
Circadian nutrition meets intermittent hypoxia: a timely fix for dysglycemia?
Obstructive sleep apnea (OSA) and type 2 diabetes mellitus are highly comorbid conditions, complicating each other’s management. Despite recent advances in our understanding of these two diseases, the treatment of OSA-induced dysglycemia and insul...
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Posted: December 18, 2025, 12:00 am
High obstructive sleep apnea hypoxic burden associates with reduced locus coeruleus structural integrity on 7T MRI in older adults
AbstractThe locus coeruleus (LC) plays important roles in sleep/wake regulation and cognitive functions. LC neurons may be particularly sensitive to neural injury and serve as an early site of accumulation pathological tau in Alzheimer’s disease. ...
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Posted: December 16, 2025, 12:00 am
Response to the letter “Post-COVID-19 insomnia beyond stress: insights from polysomnography”
Dear Editors,
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Posted: December 15, 2025, 12:00 am
Age-related widespread reorganization of whole-brain functional networks after partial sleep deprivation
AbstractAlthough partial sleep deprivation affects brain function and results in emotional and subjective sleepiness abnormalities, the changes in the brain functional configurations after partial sleep deprivation and their interaction effects wi...
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Posted: December 12, 2025, 12:00 am
Classification and clustering on nocturnal polysomnography: distinctions and overlaps between central disorders of hypersomnolence
AbstractStudy ObjectivesDifferential diagnosis of narcolepsy type 2 (NT2) from type 1 (NT1) and idiopathic hypersomnia (IH) is challenging due to overlapping symptoms. We developed an automated method using nocturnal polysomnography (nPSG) data to...
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Posted: December 4, 2025, 12:00 am
