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Frontiers in Physiology | Chronobiology section | New and Recent Articles
Environmental, social, and behavioral challenges of the human circadian clock in real-life conditions
Urban environments, in which ambient light has become a less-reliable entrainer, are challenging for the biological clock to maintain performance. As a consequence, human circadian rhythms are less robust and more variable among individuals. Asses...
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Neuroendocrine effects of the duper mutation in Syrian hamsters: a role for Cryptochrome 1
Molecular and physiological determinants of the timing of reproductive events, including the pre-ovulatory LH surge and seasonal fluctuations in fertility, are incompletely understood. We used the Cryptochrome 1-deficient duper mutant to examine t...
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Timing of diuretic administration effects on urine volume in hospitalized patients
Importance: Some medications have effects that depend on the time of day they are given. Current knowledge of the time-of-day effects of specific medications in hospitalized patients with cardiovascular disease is very limited. In hospitalized pat...
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Phenotyping of light-activated neurons in the mouse SCN based on the expression of FOS and EGR1
Light-sensitive neurons are located in the ventral and central core of the suprachiasmatic nucleus (SCN), whereas stably oscillating clock neurons are found mainly in the dorsal shell. Signals between the SCN core and shell are believed to play an...
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Delaying early morning workouts to protect sleep in two-a-day athletes
Two-a-day training is common for endurance athletes with training sessions typically beginning at 6 a.m. and 3 p.m. or 4 p.m. However, the early morning workouts could contribute to significant sleep loss, especially for night owls. Chronic sleep ...
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Contribution of membrane-associated oscillators to biological timing at different timescales
Environmental rhythms such as the daily light-dark cycle selected for endogenous clocks. These clocks predict regular environmental changes and provide the basis for well-timed adaptive homeostasis in physiology and behavior of organisms. Endogeno...
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Regulation of feeding dynamics by the circadian clock, light and sex in an adult nocturnal insect
Animals invest crucial resources in foraging to support development, sustenance, and reproduction. Foraging and feeding behaviors are rhythmically expressed by most insects. Rhythmic behaviors are modified by exogenous factors like temperature and...
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Tailored lighting intervention (TLI) for improving sleep-wake cycles in older adults living with dementia
Introduction: Sleep disturbance is a hallmark of Alzheimer’s disease and related dementias, and caregiver stress caused by patients’ nighttime wandering, injuries, and agitation are frequently at the root of decisions to move them to assisted livi...
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