This section aims to increase our understanding of the neuronal underpinnings of sleep & circadian rhythms
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Frontiers in Neuroscience | Sleep and Circadian Rhythms section | New and Recent Articles
Dynamic changes in sleep architecture in a mouse model of acute kidney injury transitioning to chronic kidney disease
IntroductionSleep disorders are common in individuals with kidney failure. Whether kidney impairment is the direct cause of sleep abnormalities is unclear, however, partly due to confounding factors including comorbidities, dialysis, and drugs.Met...
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Editorial: Long-term effects of adolescent stress, sleep deprivation, or circadian disruption on mood and anxiety
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The circadian genes are required in DAL neurons for Drosophila long-term memory formation
We previously showed that memory formation of Drosophila olfactory avoidance can be inhibited by ubiquitous, post-training, inducible disruption of the circadian system. In this report, we limit intervention to the dorsal anterior lateral neurons,...
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Role of the clock gene homolog aha-1 in the circadian system of Caenorhabditis elegans
BackgroundCircadian rhythms are endogenous and allow organisms to adapt to external daily rhythms of light, temperature and other environmental factors. Circadian rhythms are regulated by a central clock, which is based on a transcription-translat...
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Loss-of-consciousness: sources of GABAergic input to the mesopontine tegmental anesthesia area
Exposure of neurons in the brainstem mesopontine tegmental anesthesia area (MPTA) to minute quantities of GABAergic general anesthetics at clinically relevant concentrations is sufficient to induce loss-of-consciousness (LOC), while lesioning this...
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Changes of regional brain activity in frontal areas associated with cognitive impairment in obstructive sleep apnea-hypopnea syndrome patients: a resting-state fMRI study
IntroductionObstructive sleep apnea-hypopnea syndrome (OSAHS) can lead to cognitive impairment, however, its central neural mechanism is still unclear.MethodsResting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 31...
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A systematic review and meta-analysis of acoustic stimulation in the treatment of insomnia
BackgroundInsomnia is a prevalent and debilitating sleep disorder affecting approximately one-third of the global population, with 10–15% of individuals progressing to chronic insomnia. Acoustic stimulation, a promising non-pharmacological treatme...
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Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV
The dysregulation of sleep–wake patterns that occurs during aging is well documented and coincides with changes in intracellular signaling pathways that regulate sleep, such as the calcium/calmodulin-dependent protein kinase (CaMKII)/cyclic-AMP re...
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