This section aims to increase our understanding of the neuronal underpinnings of sleep & circadian rhythms
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Frontiers in Neuroscience | Sleep and Circadian Rhythms section | New and Recent Articles
Weak synchronization can alter circadian period length: implications for aging and disease conditions
The synchronization of multiple oscillators serves as the central mechanism for maintaining stable circadian rhythms in physiology and behavior. Aging and disease can disrupt synchronization, leading to changes in the periodicity of circadian acti...
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A study on feature selection using multi-domain feature extraction for automated k-complex detection
BackgroundK-complex detection plays a significant role in the field of sleep research. However, manual annotation for electroencephalography (EEG) recordings by visual inspection from experts is time-consuming and subjective. Therefore, there is a...
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Development of circadian neurovascular function and its implications
The neurovascular system forms the interface between the tissue of the central nervous system (CNS) and circulating blood. It plays a critical role in regulating movement of ions, small molecules, and cellular regulators into and out of brain tiss...
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Designing artificial circadian environments with multisensory cares for supporting preterm infants’ growth in NICUs
Previous studies suggest the importance of stable circadian environments for fetuses to achieve sound physiology and intrauterine development. This idea is also supported by epidemiological and animal studies, in which pregnant females exposed to ...
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A phosphorylation-deficient mutant of Sik3, a homolog of Sleepy, alters circadian sleep regulation by PDF neurons in Drosophila
Sleep behavior has been observed from non-vertebrates to humans. Sleepy mutation in mice resulted in a notable increase in sleep and was identified as an exon-skipping mutation of the salt-inducible kinase 3 (Sik3) gene, conserved among animals. T...
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The nucleus accumbens functional connectivity in patients with insomnia using resting-state fMRI
BackgroundThe aim of this study was to investigate the functional abnormalities between the nucleus accumbens (NAc) and the whole brain in individuals with Insomnia Disorder (ID) using resting-state functional magnetic resonance imaging (fMRI). Ad...
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Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light–dark cycles in mice
Many patients with psychiatric conditions, such as bipolar disorder and major depressive disorder, frequently experience disruptions in their sleep–wake cycles. Several case studies and clinical trials have shown that the administration of aripipr...
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