This section aims to increase our understanding of the neuronal underpinnings of sleep & circadian rhythms
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Frontiers in Neuroscience | Sleep and Circadian Rhythms section | New and Recent Articles
Sleep and circadian rhythm disruptions in animal models of temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is frequently accompanied by disruptions to sleep and circadian rhythms, which substantially contribute to disease burden. Human studies are often confounded by antiseizure medications, limiting insight into underlying...
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The ventrolateral preoptic nucleus: a multisystem integrator in sleep–wake regulation
The ventrolateral preoptic nucleus (VLPO) of the anterior hypothalamus is a major sleep-promoting region and a key component of the networks governing sleep–wake regulation. Rather than acting as a unitary “sleep center,” the VLPO is increasingly ...
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Examining circadian rhythm dysregulation using actigraphy among treatment-seeking individuals with alcohol use disorder
BackgroundIdentifying factors predictive of relapse in patients with alcohol use disorder (AUD) following a period of abstinence and/or treatment is essential to discover effective treatment plans for this disease. Previous evidence found that ind...
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Timing of exercise differentially modulates fear memory and hippocampal neurotransmitters in male rats
Exercise promotes neurogenesis and enhances memory consolidation while reducing the retention of aversive memories and anxiety-like behaviors. While our previous work found that acute exercise alters neurotransmitter concentrations, including dopa...
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A narrative review on oxytocin at the intersection of sleep, stress, and social behavior
Sleep, stress regulation, and circadian rhythms form an interdependent network that shapes cognition, emotion, and social behavior. Disruption of any component can amplify stress sensitivity and impair emotional regulation, leading to neurobehavio...
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Perioperative stellate ganglion block improves early postoperative sleep after gynecological laparoscopic surgery: a randomized controlled trial
BackgroundPostoperative sleep disturbance is highly prevalent after laparoscopic surgery and is closely associated with perioperative stress responses, impaired recovery quality, and prolonged hospital stay. However, effective interventions specif...
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Targeting the microbiota-gut-brain axis in post-stroke insomnia: a phase-dependent therapeutic framework
Post-stroke insomnia (PSI) is a critical biological barrier to neurorehabilitation afflicting over half of all stroke survivors. Traditional sedatives often force clinicians into a therapeutic dilemma between sleep efficacy and cognitive suppressi...
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Long-term follow-up of insomnia patients: symptom trajectories and predictors of treatment outcomes in a mobile-based CBT-I program
ObjectiveTo investigate the longitudinal trajectories and prognostic factors of insomnia-related symptoms over a four-year follow-up period, using pharmacotherapy combined with a mobile-based cognitive behavioral therapy (CBT-I) for insomnia inter...
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