This section aims to increase our understanding of the neuronal underpinnings of sleep & circadian rhythms
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Frontiers in Neuroscience | Sleep and Circadian Rhythms section | New and Recent Articles
Circadian and sleep–wake rhythm alterations in isolated REM sleep behavior disorder: biomarkers of prodromal α-synucleinopathy
Growing evidence highlights a tight interplay linking circadian and sleep–wake disturbances to the pathophysiology of neurodegenerative disorders. In α-synucleinopathies, three key points have emerged: (1) circadian and sleep–wake disruptions may ...
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Mechanism study of exercise intervention on circadian disruption in Alzheimer’s disease
Alzheimer’s disease (AD) induces profound circadian disruption—characterized by suprachiasmatic nucleus (SCN) degeneration, Aβ and tau pathology, and aberrant melatonin secretion which results in fragmented sleep–wake cycles and cognitive decline....
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Exercise as a modulator of gut microbiota for improvement of sleep quality: a narrative review
Sleep quality is a cornerstone of physical and mental well-being, yet millions of individuals worldwide suffer from chronic sleep disturbances. Recent developments in microbiome research have shown that the microbiota–gut–brain axis regulates slee...
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Study on the sleep–wake circadian rhythm and phenotypic characteristics in the acute phase of hemorrhagic stroke
ObjectiveTo investigate the sleep–wake circadian rhythm and phenotypic characteristics in patients with acute intracerebral hemorrhage (ICH), and to explore the relationship and potential mechanisms between sleep–wake phenotypes and circadian rhyt...
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Research on the effect of TMS on insomnia patients: EEG changes and prognostic modeling
ObjectiveInsomnia (ID) is the most common clinical disorder afflicting people of all ages, races, and social classes. This study was to explore changes in the brain’s nervous system of insomnia patients after TMS treatment and construct a prognost...
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Remarkable therapeutic effects of methylphenidate in periodic limb movement disorder comorbid with excessive daytime sleepiness: a case report
BackgroundPeriodic limb movement disorder (PLMD) is a sleep-related movement disorder, which may be accompanied by a complaint of excessive daytime sleepiness (EDS). With this study, we reported a clinical therapy process up to 2.5 years follow-up...
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Exercise, circadian rhythms, and muscle regeneration: a path to healthy aging
The circadian system regulates core physiological processes, including muscle regeneration, protein synthesis, and cellular homeostasis. Disruptions in circadian rhythms contribute to impaired muscle function in older adults, with age-related decl...
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