Articles cover sleep & circadian rhythms disorders from bench research to clinical reviews
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Frontiers in Neurology | Sleep Disorders section | New and Recent Articles
The optimal dose of Ramelteon for the better treatment adherence of delayed sleep–wake phase disorder: a dropout rate study
BackgroundEvidence regarding the effectiveness of melatonin receptor agonists in treating delayed sleep–wake phase disorder (DSWPD) remains limited. This study aimed to determine the optimal dose of ramelteon, a melatonin receptor agonist, for the...
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Exploring the causes of augmentation in restless legs syndrome
Long-term drug treatment for Restless Legs Syndrome (RLS) patients can frequently result in augmentation, which is the deterioration of symptoms with an increased drug dose. The cause of augmentation, especially derived from dopamine therapy, rema...
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Sleep in marathon and ultramarathon runners: a brief narrative review
IntroductionSleep is considered a fundamental biological function in humans necessary for recovery from daily physical activities. Considering the increasing popularity of long-distance running and participation in races such as marathons and ultr...
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Auricular acupuncture for persistent insomnia and anxiety associated with COVID-19: a case report
The coronavirus disease 2019 (COVID-19) has been associated with various psychological symptoms. We report a case of a female patient who was diagnosed with persistent insomnia and anxiety associated with COVID-19, which was successfully treated w...
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The association between serum total folic acid concentration and severe difficulty falling asleep in US adults: NHANES 2005–2008
ObjectiveThe present study aimed to explore the correlation of serum total folic acid concentration with severe difficulty falling asleep among US adults.MethodsCross-sectional data were collected from the National Health and Nutrition Examination...
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Quantitative sleep electroencephalogram and cognitive performance in Parkinson’s disease with and without rapid eye movement sleep behavior disorder
IntroductionParkinson’s disease (PD) patients with REM sleep behavior disorder (RBD) are at greater risk for cognitive decline and RBD has been associated with alterations in sleep-related EEG oscillations. This study evaluates differences in slee...
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Associations between perioperative sleep patterns and clinical outcomes in patients with intracranial tumors: a correlation study
ObjectiveAlthough the quality of perioperative sleep is gaining increasing attention in clinical recovery, its impact role remains unknown and may deserve further exploration. This study aimed to investigate the associations between perioperative ...
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Comparison of three measures for insomnia in ischemic stroke patients: Pittsburgh sleep quality index, insomnia severity index, and Athens insomnia scale
ObjectiveThis study investigated the consistency and determined the optimal threshold values of three scales in the diagnosis of insomnia of ischemic stroke (IS) patients.MethodsParticipants in this study consisted of 569 acute IS patients. All 56...
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