Articles cover sleep & circadian rhythms disorders from bench research to clinical reviews
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Frontiers in Neurology | Sleep Disorders section | New and Recent Articles
Nomogram for predicting early olfactory dysfunction in obstructive sleep apnea-hypopnea syndrome: a multicenter-based study
ObjectiveTo develop and validate a clinical prediction model for olfactory dysfunction in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), evaluating the combined predictive value of polysomnography (PSG) parameters and clinical sy...
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Efficacy of auricular point-vagus nerve stimulation in adolescent insomnia patients and the brain function regulation mechanisms: a study protocol for an experimental, randomized, controlled clinical trial
BackgroundAdolescent insomnia is a prevalent issue with significant implications for mental and physical well-being. Given the increasing incidence of sleep disorders, there is an urgent need for safe and efficient treatment modalities, particular...
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Synergistic acupuncture and neuromodulation for chronic insomnia: a structured narrative review with systematic search and future directions
Insomnia represents a significant global public health issue, affecting approximately 10% of adults with chronic symptoms and up to 20% with intermittent episodes. Closely associated with chronic diseases such as depression, anxiety, and cardiovas...
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Detailed evaluation of sleep apnea using heart rate variability: a machine learning and statistical method using ECG data
BackgroundSleep apnea is a common sleep disorder associated with high degree of autonomic dysfunction and increased cardiovascular risk. Traditional diagnostic methods such as polysomnography (PSG) are costly, time-consuming, and sometimes unavail...
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Elevated remnant cholesterol impairs sleep characteristics in individuals with newly diagnosed moderate-to-severe obstructive sleep apnea: a cross-sectional case–control study
BackgroundAlthough obstructive sleep apnea (OSA) is widely recognized as a common contributor to disruptions in sleep and lipid metabolism, there is still a lack of concrete evidence to substantiate this correlation. Remnant cholesterol (RC) is in...
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Arginase and ceruloplasmin activity in the serum of patients with polysomnography-detected sleep bruxism
BackgroundArginase and ceruloplasmin are enzymes of redox balance involved in the metabolism of nitric oxide. Arginase competes with nitric oxide synthase (NOS) for L-arginine and hence plays a crucial role in the arginase/NOS balance of maintaini...
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Efficacy of electroacupuncture on insomnia disorder in older adults: study protocol for a multicentre randomised controlled trial
IntroductionInsomnia disorder is highly prevalent among older adults and is associated with significant adverse effects on both physical and psychological health. The use of hypnotic medications in this population is often accompanied by undesirab...
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Non-pharmacological interventions for sleep in older adults: an umbrella review and evidence map of randomized controlled trials
BackgroundSleep health is a critical determinant of older adults’ physical, cognitive, and emotional well-being, yet pharmacological treatments for sleep disturbances carry substantial risks.ObjectiveThis umbrella review aims to synthesize evidenc...
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