Articles cover sleep & circadian rhythms disorders from bench research to clinical reviews
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Frontiers in Neurology | Sleep Disorders section | New and Recent Articles
Arginase and ceruloplasmin activity in the serum of patients with polysomnography-detected sleep bruxism
BackgroundArginase and ceruloplasmin are enzymes of redox balance involved in the metabolism of nitric oxide. Arginase competes with nitric oxide synthase (NOS) for L-arginine and hence plays a crucial role in the arginase/NOS balance of maintaini...
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Efficacy of electroacupuncture on insomnia disorder in older adults: study protocol for a multicentre randomised controlled trial
IntroductionInsomnia disorder is highly prevalent among older adults and is associated with significant adverse effects on both physical and psychological health. The use of hypnotic medications in this population is often accompanied by undesirab...
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Non-pharmacological interventions for sleep in older adults: an umbrella review and evidence map of randomized controlled trials
BackgroundSleep health is a critical determinant of older adults’ physical, cognitive, and emotional well-being, yet pharmacological treatments for sleep disturbances carry substantial risks.ObjectiveThis umbrella review aims to synthesize evidenc...
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Relationship between cortical activation and sleep quality in cerebral small vessel disease patients: a functional near-infrared spectroscopy (fNIRS) study
BackgroundSleep disturbance is common in patients with cerebral small vessel disease (CSVD). The impact of insomnia on cortical activation in CSVD patients and its association with sleep quality remains unclear. Our study used functional near-infr...
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Identification and molecular mechanism of palmitoylation-related biomarkers in obstructive sleep apnea
IntroductionPalmitoylation influences patients with obstructive sleep apnea (OSA) by modulating amyloid-β production. However, the involvement of palmitoylation-related genes (PRGs) in OSA remains unclear. This study aims to investigate this mecha...
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Prevalence and risk factors of depression in Korean patients with untreated obstructive sleep apnea
IntroductionThis study investigated the prevalence and risk factors of depression among Korean adults with untreated obstructive sleep apnea (OSA).MethodsA total of 887 adults newly diagnosed with OSA at a university hospital underwent overnight p...
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CPAP modulation of sleep microstructure (N2-SSD and REM-AHI) as predictors of neurological recovery in ischemic stroke patients with moderate-to-severe OSA
BackgroundThere is a disease spectrum of ischemic stroke (IS) and obstructive sleep apnea (OSA), which are often comorbid in the same patient and consequently increases prognostic risk. Continuous positive airway pressure (CPAP) therapy is the pri...
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